Endogenous melatonin, plays an important role in circadian regulatregulation of sleep.

Melatonin is a natural hormone secreted by the human body that regulates sleep better than sleeping pills, which are much more aggressive when it alters the human biological clock.
By: Dens
 
May 11, 2011 - PRLog -- Melatonin is currently being widely used by the pharmaceutical industry to design synthetic drugs derived from it, which pose a very interesting therapeutic tool for treating sleep disorders. The European Medicines Agency (EMEA) in 2007 authorized the use of melatonin for this type of therapy, after years of debate on the desirability of this measure.

Melatonin is a natural hormone secreted by the human body that regulates sleep better than sleeping pills, which are much more aggressive when it alters the human biological clock.

This is evidenced by results of research conducted by professors at the Institute of Biotechnology, Biomedical Research Center at the University of Germaine, who have done an analysis of the properties of this natural hormone secreted by pineal gland.

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The time change occurs every year around this time is more common in older people taking sedatives and / or antidepressants, as he recalled the neurologist USP San.

However, the situation is "temporary" and it is normal for ten days has passed, otherwise Yusta  recommended to go to consultation.

Also among the tips offered by this specialist better adaptation is not to alter the circadian rhythm or biological and still maintain the hours of night rest and activity, as had been done.

It should also ensure proper hydration (drink 2 to 3 liters of water a day) and avoid taking stimulants such as tea or coffee at times, especially late in the afternoon.

It also notes that it should also avoid long naps over 30 minutes and should seek to conduct activities that require more focus on the times being more clear.

For its part, the people who get migraines have to follow the recommendations for treating this disease because the episodes can be intensified during the period of adaptation to time shift.


Researchers at the University of Granada claim that melatonin is a very effective chronobiotic in the treatment of chronobiological alterations of the sleep / wake ", though she says that his administration" should be done at certain times of day, which induce an advance or a phase lag as appropriate. " Therefore, the scientists point out that "the lack of effect of melatonin is associated, most often, to inadequate management."

The authors of this paper, published in the 'Journal of Neurology', asserts that the endogenous melatonin, secreted by the human body itself, plays an important role in circadian regulation of sleep ", whereas exogenous melatonin, given as drug, "influences and aspects of sleep latency and quality."

In fact, the ability of melatonin to readjust the biological clock has been studied in blind individuals, and they can not use photoperiod information to activate the endogenous pacemaker secretes melatonin at night. Scientists say that the administration of melatonin for 24 hours restored the rhythms in these people, including the sleep / wake, synchronizing them to a period of 24 hours.

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Source:Dens
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Tags:Melatonin Side Effects, Melatonin Depression, Melatonin For Sleep
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