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Follow on Google News | AnaSpec Introduces New SensoLyte® GSH and GST Assay KitsAnaSpec has introduced two new Glutathione (GSH) related kits - the SensoLyte® Glutathione Cellular Assay Kit and the SensoLyte® GST Activity Assay Kit
By: Albert O. Hong AnaSpec has introduced two new Glutathione (GSH) related kits - the SensoLyte® Glutathione Cellular Assay Kit and the SensoLyte® GST Activity Assay Kit to complement the colorimetric and fluorimetric SensoLyte® Total GSH assay kits. The SensoLyte® Glutathione Cellular Assay Kit provides a sensitive fluorescent assay for determination of the glutathione levels in cell or tissue extracts. The kit contains a non-fluorescent substrate, which selectively reacts with GSH in reaction catalyzed by glutathione S-transferase (GST) to form a fluorescent glutathione adduct. The resulting blue fluorescence can be monitored at Ex/Em= 390 nm/480 nm. The SensoLyte® GST Activity Assay Kit detects total GST activity in plasma, cell and tissue lysates. It contains a non-fluorescent substrate for GST, which upon conjugation with reduced GSH generates bright fluorescence that can be detected at Ex/Em= 390nm/480 nm. Glutathione S-transferases (GST) belong to a family of enzymes that is involved in detoxification and toxification mechanisms. They act via conjugation of reduced glutathione (GSH) with numerous substrates such as pharmaceuticals and environmental pollutants.1- References 1. Sheenan D. et al. Biochem J. 360, 1 (2001). 2. Rushmore T. et al. J. Biol. Chem. 268, 11475 (1993). 3. Estonius M. et al. Eur. J. Biochem. 260, 409 (1999). 4. Hayes D. J et al. Annu. Rev. Pharmacol. Toxicol. 45, 51 (2005). About AnaSpec AnaSpec is a leading provider of integrated proteomics solutions to the world’s largest biotech, pharmaceutical, and academic research institutions. With a vision for innovation through synergy, AnaSpec focuses on three core technologies: AnaSpec recently joined forces with Eurogentec to provide an even broader spectrum of products and services to serve the worldwide life science community. For more information visit www.anaspec.com About Eurogentec Eurogentec is a leading global supplier of innovative reagents, kits, specialty products and custom services to scientists in the life science, biotechnology, pharmaceutical and diagnostic markets. Eurogentec provides a wide range of expertize in small- and large-scale DNA, RNA, PCR and qPCR kits, peptide synthesis and antibody supply for research applications. Our ISO13485:2003- Eurogentec is a privately held company headquartered in Liège, Belgium, with subsidiaries in North America, France, Germany, the UK, the Netherlands and Switzerland and has additional production facilities in North America, Japan and Singapore. Eurogentec employs 400+ people globally. For more information visit www.eurogentec.com # # # AnaSpec, Inc. is a leading provider of integrated proteomics solutions™ for worldwide life science research. AnaSpec offers expertise in three primary technologies: End
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