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Follow on Google News | AnaSpec Introduces New SensoLyte® uPA & tPA Assay KitsAnaSpec is pleased to introduce two plasminogen activator assay kits – the SensoLyteÒ AFC Urokinase (uPA) Assay Kit and the SensoLyteÒ AMC tPA Assay Kit.
By: Albert O. Hong Plasminogen activator (PA), classified immunological into urokinase-type PA (uPA) and tissue-type PA (tPA), converts the zymogen plasminogen to the active, broad-spectrum serine protease plasmin.1 Plasmin, in turn, mediates the pericellular proteolysis of extracellular matrix components and activates other proteases such as matrix metalloproteinases and collagenases that lead to the further degradation and remodeling of the extracellular matrix.2,3 AnaSpec is pleased to introduce two plasminogen activator assay kits – the SensoLyteÒ AFC Urokinase (uPA) Assay Kit and the SensoLyteÒ AMC tPA Assay Kit. These kits, optimized for inhibitor screening, contain high-performance fluorogenic substrates which exhibit high reactivity and low background signal. The AFC (7-amino-4-trifluoromethylcoumarin) References: 1. Christman, JK. Research Monographs in Cell and Tissue Physiology, 2. Proteinases in Mammalian Cells and Tissues. AJ. Barett, ed. North Holland Publishing Co. Amsterdam 90-149 (1977). 2. Duffy, MJ. Curr Pharm Des. 10:39 (2004). 3. Castellino, FJ. et al. Thromb Haemost. 93:647 (2005). About AnaSpec AnaSpec is a leading provider of integrated proteomics solutions to the world’s largest biotech, pharmaceutical, and academic research institutions. With a vision for innovation through synergy, AnaSpec focuses on three core technologies: AnaSpec recently joined forces with Eurogentec to provide an even broader spectrum of products and services to serve the worldwide life science community. For more information visit www.anaspec.com About Eurogentec Eurogentec is a leading global supplier of innovative reagents, kits, specialty products and custom services to scientists in the life science, biotechnology, pharmaceutical and diagnostic markets. Eurogentec provides a wide range of expertize in small- and large-scale DNA, RNA, PCR and qPCR kits, peptide synthesis and antibody supply for research applications. Our ISO13485:2003- Eurogentec is a privately held company headquartered in Liège, Belgium, with subsidiaries in North America, France, Germany, the UK, the Netherlands and Switzerland and has additional production facilities in North America, Japan and Singapore. Eurogentec employs 400+ people globally. For more information visit www.eurogentec.com # # # AnaSpec, Inc. is a leading provider of integrated proteomics solutions™ for worldwide life science research. AnaSpec offers expertise in three primary technologies: End
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