Cystic Fibrosis (CF) Therapeutics - Pipeline Assessment and Market Forecasts to 2018

Aug. 25, 2011 - PRLog -- GlobalData’s analysis suggests that the global Cystic Fibrosis (CF) therapeutics market valued at $622.9m in 2005, and grew at a Compound Annual Growth Rate (CAGR) of 12.0% to reach $1,096.3m in 2010. GlobalData forecasts that the global CF therapeutics market will grow at a high CAGR of 10.7% over the next eight years, to reach $2,472.8m by 2018. This growth is primarily attributed to an increase in the annual cost of treatment due to the expected launch of novel, premium priced therapies VX-770 and Ataluren during the forecast period. VX-770 is expected to be launched in late 2012 and Ataluren in 2014. An increase in the treatment seeking population due to an increase in the life expectancy and increasing awareness leading to diagnosis at an early stage will drive the CF therapeutics market. The current competition in the CF therapeutics market is weak, primarily dominated by TOBI (inhaled tobramycin), Pulmozyme (dronase alpha), pancreatic enzyme and many other antibiotics such as meropenem, ceftazidime and hypertonic saline solution, which provide only symptomatic treatment in CF.

Novartis AG (Novartis) and F. Hoffmann–La Roche Ltd. (Roche) are the leading competitors in the global
CF therapeutics market. Together, these companies account for a major share in the global CF therapeutics market. However, Cystic Fibrosis Foundation Therapeutics (CFFT) and companies such as
Gilead Sciences, Vertex Pharma, Pharmaxis and Pari Pharma, with some technologically advanced products in their pipeline portfolios, are expected to attract the majority of investors’ attention in near
future.

Only four key products (TOBI, Pulmozyme, Cayston (aztreonam inhalation) and Creon (pancrelipase) are
approved for the treatment of CF. Cayston and Creon have been recently approved for the treatment of
CF, suggesting that current competition in the CF therapeutics market is weak. The future could see more competition following multiple product launches by the leading and emerging manufacturers, who are concentrating on novel therapies such as Cystic Fibrosis Transmembrane Conductance regulator (CFTR), potentiator and corrector. It is a gene therapy which acts on specific G551D mutation and nonsense mutation of CF. It functions as an ion channel across the cell membrane found in tissues that produce mucus, sweat, saliva, tears and digestive enzymes. In addition to this, novel formulations, anti-inflammatory agents, mucolytics and pancreatic enzyme therapies are being developed for the treatment of CF.

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Industry analysis specialist, GlobalData, has released its new report, “Cystic Fibrosis (CF) Therapeutics
- Pipeline Assessment and Market Forecasts to 2018”. The report is an essential source of information
on the global Cystic Fibrosis therapeutics market, and provides analysis of a number of key areas. The
report identifies the key trends shaping and driving the global Cystic Fibrosis therapeutics market and provides insights into the current competitive landscape and emerging companies expected to significantly alter the market positioning of current market leaders. Most importantly, the report provides valuable insights into the pipeline products within the global Cystic Fibrosis sector. This report is built using data and information sourced from proprietary databases, primary and secondary research and inhouse analysis by GlobalData’s team of industry experts.

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