Neuropathic Pain Therapeutics - Pipeline Assessment and Market Forecasts to 2018

The Neuropathic Pain Market is Forecast to Show Significant Growth until 2018
By: Rajesh Gunnam
 
Sept. 9, 2011 - PRLog -- GlobalData estimated the global neuropathic pain market to be worth $4.8 billion in 2010. It is expected to grow at a compound annual growth rate (CAGR) of approximately 9.6% from $4.8 billion in 2010 to $10 billion in 2018. This significant growth is primarily attributed to the:

•   Increasing patient pool for neuropathic pain due to the increase in the prevalence of co-morbid
conditions, such as herpes zoster, multiple sclerosis, trigeminal neuralgia, diabetes and migraine.

•   Clinical development and preferential uptake of newer disease modifying agents, such as Zenvia
(AVP-923) and AS-3201 (ranirestat), which are expected to positively impact and change the future Treatment paradigm for neuropathic pain.

GlobalData analysis suggests that the current competition in the neuropathic pain market is strong, led by Pfizer’s Lyrica and Eli Lilly’s Cymbalta. There are only five drugs that are approved by the US Food and
Drug Administration (FDA) and European Medicines Agency (EMA) for the treatment of neuropathic pain: Lyrica (pregabalin), Cymbalta (duloxetine), Neurontin (gabapentin), Lidoderm (lidocaine 5% patch)
(approved under the trade name Versatis in Europe) and recently, Qutenza (capsaicin 8% patch). Lyrica,
Cymbalta, Lidoderm and Qutenza currently have a significant presence in the market. Moreover, the presence of gabapentin and other generic drugs has intensified the competition. Pfizer remains the market leader in the neuropathic pain market, followed by Eli Lilly. There is competition between Lyrica
and Cymbalta in the treatment of pain associated with diabetic peripheral neuropathy (DPN)

GlobataData’s research indicates that the treatment of neuropathic pain relies on a limited number of
therapies. The currently available therapies provide partial pain relief to the patient instead of eradicating the underlying cause of the pain. Although the current market is reasonably well served, the market still needs disease modifying therapies offering better results in terms of safety and efficacy, as well as a cure for the underlying cause of the pain. Achieving these objectives will address the existing unmet need in the market.

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GlobalData found that the available treatment options are moderately successful in meeting the market
demand. Although the current neuropathic pain therapeutics market has FDA approved drugs such as
SNRIs (serotonin–norepinephrine re-uptake inhibitors) and tricyclic antidepressants (TCAs), these drugs
only have moderate efficacy and safety profiles. The current therapies are competing to provide a greater than or equal to 50% reduction in pain. A greater than or equal to 30% reduction in pain is considered to be clinically significant. Providing partial relief (a greater than or equal to 50% reduction in pain) has been the target endpoint for products in the market. However, there is a need for a product that can be more efficacious in reducing the pain, offering long term pain relief with better safety. There is potential in the market for any new entrant that will cater to these unmet needs and there is enormous opportunity for any drug that can offer better long-term efficacy and safety.

GlobalData, the industry analysis specialist, has released its new report, “Neuropathic Pain Therapeutics - Pipeline Assessment and Market Forecasts to 2018”. The report is an essential source of information and analysis on the global neuropathic pain therapeutics market. The report identifies the key trends shaping and driving the global neuropathic pain therapeutics market. The report also provides insights on the prevalent competitive landscape and the emerging players expected to significantly alter the market positioning of the current market leaders. Most importantly, the report provides valuable insights on the pipeline products within the global chronic pain sector. This report is built using data and information sourced from proprietary databases, primary and secondary research and in-house analysis
by GlobalData’s team of industry experts.

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Source:Rajesh Gunnam
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