Report on MS MRM Technology in Quantitative Analysis and Application in Creative Proteomics

SHIRLEY, N.Y. - March 8, 2016 - PRLog -- With years of experience on MS MRM technology, scientists in Creative Proteomics made a report on its quantitative analysis and applications. And this report is also known as that of aqua mass spectrometry in Creative Proteomics.

Theory

MRM is a kind of mass spectrometry, which is based on the known or assumed reactive ion information to collect mass spectrometry information selectively, record the ion complied with the rules and avoid the interference from other ions.

Features of MS MRM technology

1.High sensitivity

This technology can pass through two-stage ion-selective, excluding a large number of interfering ions to reduce the chemical background and increase the noise ratio of target detection in order to achieve the sensitivity goal.

2.Good reproducibility

During the process of information collection, researchers can avoid the interference of ionized of analyte molecules, MS signals’ inhibition and collision fragmentation of endogenous. So that reproducibility will be improved significantly.

3.High accuracy

With the specificity of MRM technology, ion scan analysis can be increased continuously to gain the mass spectrometry (MS/MS) fragmentation data with high resolution. Compared to full scan and neutral loss scan mode, this technology can reduce the false-positive results rate during the analysis process so that the accuracy can be ensured.

4.High throughput

By using the most advanced MS system, MRM technology can analyze nearly 300 pairs of ions in each working cycle. This advantage allows researchers to study on various modifications and abundance change. What’s more, it can meet some research requirements of proteomics.

These are some details about this report on 8th. Scientists in Creative Proteomics also declaimed that study on MS MRM technology will be still carried on.

More information: http://www.creative-proteomics.com/services/absolute-quan...