Creative Biostructure Provides Solutions for Drug Design with Structure-based Drug Design Platform

June 7, 2022 - PRLog -- Creative Biostructure Drug Discovery, a sub-brand of Creative Biostructure that applies its expertise in structural biology and membrane proteins to the drug discovery process, has developed MagHelix™ Structural Biology and SBDD Platform (https://drug-discovery.creative-biostructure.com/maghelix-structural-biology-and-sbdd-platform-p58) that covers all the mainstream technologies needed to successfully determine the 3D structure of biological macromolecules.

Structure-based drug design (SBDD) is a molecular recognition-based drug design approach that starts with the three-dimensional (3D) structure of ligands and targets. In this drug discovery strategy, the 3D structure of the target is essential and can be obtained by structural biology techniques or homology modeling, followed by experimental or computational methods to study the interaction pattern of the ligand with the receptor. On this basis, reasonable drug design was performed.

Creative Biostructure offers Structure-Based Drug Design (SBDD) Service that can determine the 3D structure of biological macromolecules using its MagHelix™ Structural Biology and SBDD Platform, which covers all mainstream technologies.

Some of its capabilities include:

Target Structure Determination

Ligand Library Design and Preparation (https://drug-discovery.creative-biostructure.com/maghelix...)

Molecular Docking and Scoring

Molecular Dynamics Simulation

Structure-Based Virtual Screening (https://drug-discovery.creative-biostructure.com/structur...)

Target-Ligand Binding Pattern Determination

Relying on this platform, Creative Biostructure can provide one-stop gene-to-protein and gene-to-structure solutions. Over the decades, scientists at Creative Biostructure have accumulated a wealth of experience in the structural analysis of targets such as receptors, enzymes, ion channels, antigens, and viruses.

"Depending on the specific project, to obtain high-resolution structures, we support the combined application of X-ray crystallography, Cryo-EM and NMR spectroscopy. Creative Biostructure welcomes industrial and academic researchers from around the world with drug discovery needs to use our MagHelix ™ Structural Biology and SBDD platforms for drug discovery projects." said Joanna, the chief marketing staff at Creative Biostructure.

Visit https://drug-discovery.creative-biostructure.com/maghelix-structural-biology-and-sbdd-platform-p58 to know more detailed information about the MagHelix™ Structural Biology and SBDD Platform offered by Creative Biostructure Drug Discovery.