BOC Science Launch First Pharmaceutical Grade Purity - Polysialic Acid Sodium Salt

SHIRLEY, N.Y. - April 29, 2024 - PRLog -- The leading chemical supplier BOC Science announced the launch of the world's first pharmaceutical-grade purity of sodium hyaluronate, and currently, the product has been applied in research on drug delivery systems.

Polysialic Acid Sodium Salt is a linear oligosaccharide containing α-2,8-linked sialic acid. Latest research found out, Polysialic Acid Sodium Salt plays crucial roles in various biological processes, particularly in brain development, tumor progression, and immune response.

One studies suggest Polysialic Acid Sodium Salt plays a significant role in brain development and synaptic plasticity. Its alteration has been linked to neurodevelopmental predispositions to psychiatric diseases like schizophrenia, bipolar disorder, and autism.

The other studies found out Polysialic Acid Sodium Salt's involvement in OPC (oligodendrocyte precursor cell) differentiation and myelin formation implies that modulating its levels could aid in myelin repair therapies. This could be particularly beneficial in diseases where myelin degeneration is a key feature, offering a novel approach to promote remyelination and neuroprotection.

These applications indicate that Polysialic Acid Sodium Salt is not just a structural element but also plays dynamic roles in various neurobiological processes, making it a promising target for medical interventions in psychiatric and neurodegenerative disorders.

Due to its primarily fermentation-derived nature, it inevitably contains higher levels of endotoxins. Additionally, the molecular weight of Polysialic acid sodium salt is very close to that of endotoxins, and Polysialic acid sodium salt is also a polymer. These factors make it extremely challenging to remove endotoxins.

BOC Science's research and development team conducted repeated studies and experiments, ultimately adopting a special technique, Size Exclusion Chromatography, to successfully reduce the endotoxin content of Polysialic acid sodium salt to nearly zero, achieving pharmaceutical-grade purity. Currently, BOC Science is the only entity globally to have obtained this filtration technology, and only Polysialic acid sodium salt produced by BOC Science can achieve pharmaceutical-grade purity.

Currently, Polysialic acid sodium salt is being produced in GMP workshops and applied in the development of drug delivery systems.

About BOC Science:

BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies.

For more information, please visit our website: www.bocsci.com