Phospho-c-Cbl (Tyr774) Rabbit Antibody PE Conjugate

SAN DIEGO - Oct. 2, 2024 - PRLog -- Phospho-c-Cbl (Tyr774) Rabbit Antibody PE Conjugate specifically binds to phosphorylated c-Cbl protein at tyrosine 774. It is conjugated to phycoerythrin for detection of phosphorylated c-Cbl in cells using flow cytometry or fluorescence microscopy. Commonly used in research to study signaling pathways involving c-Cbl protein phosphorylation. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

Phospho-c-Cbl (Tyr774) Rabbit Antibody PE Conjugate
Catalog number: B2018426
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 Tests
Molecular Weight or Concentration: N/A
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: 2-8 °C
Keywords: E3 ubiquitin-protein ligase CBL, Casitas B-lineage lymphoma proto-oncogene, Proto-oncogene c-Cbl, RING finger protein 55, RING-type E3 ubiquitin transferase, Signal transduction protein CBL, CBL2, RNF55
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Nadeau SA, An W, Mohapatra BC, Mushtaq I, Bielecki TA, Luan H, Zutshi N, Ahmad G, Storck MD, Sanada M, Ogawa S, Band V, Band H. Structural Determinants of the Gain-of-Function Phenotype of Human Leukemia-associated Mutant CBL Oncogene J Biol Chem. 2017 Mar 3;292(9):3666-3682.
2: Wybenga-Groot LE, Tench AJ, Simpson CD, Germain JS, Raught B, Moran MF, McGlade CJ. SLAP2 Adaptor Binding Disrupts c-CBL Autoinhibition to Activate Ubiquitin Ligase Function J Mol Biol. 2021 Apr 16;433(8):166880.

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