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Follow on Google News | Nonalcoholic Steatohepatitis (NASH) TherapeuticsThe NASH Therapeutics Market is forecast to Show Marginal Growth until 2018
By: Rajesh Gunnam over the next eight years, to reach $2,008m by 2018. This steady growth is primarily attributed to the increasing prevalence of NASH due to an increase in the prevalence of co-morbid conditions such as diabetes, obesity and hyperlipidemia, as well as increasing awareness among patients and physicians, which will lead to an increase in the diagnosed and treated patient pool. Off-label usage of antioxidants, anti-diabetes drugs, anti-obesity drugs and antihyperlipidemics is likely to continue as no specific therapies are likely to get approval through the forecast period up to 2018 GlobalData’s research indicates that the current competition in the NASH market is weak. The market lacks any therapies approved by the FDA (Food and Drug Administration) GlobalData identified that the pipeline for NASH is weak. Clinical research activity in the NASH pipeline is mainly focused in Phase II. The late stage pipeline for NASH is weak, with no molecules in development with novel mechanisms of action. Phase II has a few novel molecules, such as Raptor’s DR Cysteamine, Gilead Science’s GS 9450, Enzo Biochem’s EGS21 and NasVax’s anti-CD3 monoclonal antibody, which have shown promising results. However, there seems to be only a limited possibility that these molecules could be approved for the treatment of NASH by 2018. For Sample Pages, please click or add the below link to your browser: http://www.globaldata.com/ The NASH market has significant unmet need because the current market has no specific approved products to treat the condition. When considering the pipeline, Phase II trial of ASP9831 was discontinued by Astellas Pharma Inc. as ASP9831 was not able to achieve expected effects on liver tests. Similarly, Olesoxime (TRO19622), a Phase II product, whose development was halted by Trophos SA due to high variability in the pre-treatment values for the primary endpoint. This implies that limited knowledge of the pathology of the disease has increased challenges in drug development for NASH treatment. Due to concerns related to the safety and efficacy, the off-label drugs currently in the market do not serve the huge unmet need that exists. Thus, NASH continues to present opportunities for novel pipeline candidates. GlobalData, the industry analysis specialist, has released its new report, “Nonalcoholic Steatohepatitis (NASH) Therapeutics - Pipeline Assessment and Market Forecasts to 2018”. The report is an essential source of information and analysis on the global NASH market. The report identifies the key trends shaping and driving the global NASH market. The report also provides insights on the prevalent competitive landscape and the emerging players expected to significantly alter the market positioning of the current market leaders. Most importantly, the report provides valuable insights on the pipeline products within the global NASH sector. This report is built using data and information sourced from proprietary databases, primary and secondary research and in-house analysis by GlobalData’s team of industry experts. For further details, please click or add the below link to your browser: http://www.globaldata.com/ Visit our report store: http://www.globaldata.com/ For more details contact: pressreleases@ North America: +1 646 395 5477 Europe: Asia Pacific: # # # GlobalData is a global market intelligence services company providing information research and analysis products and services. End
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