Acne Therapeutics - Pipeline Assessment and Market Forecasts to 2018

The Acne Therapeutics Market Expected to Show Slow Growth Until 2018
By: Rajesh Gunnam
 
Aug. 25, 2011 - PRLog -- The global acne therapeutics market valued $2.8 billion in 2010 and is estimated to reach a value of $3.0
billion by 2018, after increasing at a compound annual growth rate (CAGR) of 0.9%. The slow revenue
growth is attributed to the entry of generics and the increased acceptance of alternative therapies such as photodynamic therapy (PDT) and Ultraviolet (UV)/blue light therapy for the treatment of acne. The market currently offers several products which treat acne by targeting different etiologic factors involved in the development of the condition. Solodyn (minocycline hydrochloride) currently dominates the acne therapeutics market, followed by Doryx (doxycycline). The acne therapeutics market is experiencing a shift towards combination products, using two or more effective acne treatments. The currently marketed combination products, such as Duac (clindamycin phosphate and benzoyl peroxide) and Ziana (clindamycin phosphate and tretinoin), are expected to steadily increase revenue generation. The patent expiries of Epiduo (benzoyl peroxide and adapalene) in late 2011 and Duac in 2014 will also restrain the growth of the acne therapeutics market during the forecast period. During the review period, Accutane (tretinoin) was withdrawn from the acne therapeutics market due to severe adverse events such as inflammatory bowel disease (IBD), ulcerative colitis and Crohn’s disease identified with prolonged usage of Accutane.

The acne therapeutics market is largely genericized and is adequately served by the currently marketed
drugs. The majority of the pipeline products in the acne therapeutics market consist of combination products, and there are very few first-in-class molecules in the late stages of clinical development. Increases in the global population and an increase in the prescription rate are expected to sustain the growth of the acne therapeutics market during the forecast period. With the recent characterization of
acne as a chronic disease, research and development (R&D) needs to be prioritized to study the pathology of acne. This will facilitate the identification of new molecules with novel disease targeting mechanisms of action for clinical development.

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GlobalData assessed the current competitive landscape for acne drugs and found that competition is
strong. The market has several therapeutic options for the treatment of mild, moderate and severe acne, which include antibacterial Propionibacterium acne protein synthesis inhibitors, anti-inflammatory drugs and excessive sebum production inhibitors. Also included are drugs with selective affinity for nuclear retinoic acid receptors. Largely, treatments are based on attempts to reduce inflammatory responses, suppress bacterial growth and lower new comedone formation.

The top selling acne therapeutics drugs have comparable efficacy levels and safety profiles, with only
marginal differences, which have further intensified competition in the market. As the patents for the top selling drugs, Solodyn and Doryx, are set to expire in 2018 and 2022 respectively, the revenue generated by the acne therapeutics market is expected to demonstrate slow growth until 2018. The revenue from combination products, such as Ziana and Duac, are also predicted to contribute to the growth in the acne therapeutics market. New entrants will need to exhibit superior efficacy and safety profiles compared to currently marketed products in order to gain momentum for market growth.
GlobalData, the industry analysis specialist, has released its new report, “Acne Therapeutics - Pipeline
Assessment and Market Forecasts to 2018”. The report is an essential source of information and analysis on the global Acne Therapeutics market. The report identifies the key trends shaping and driving the global Acne Therapeutics market. The report also provides insights on the prevalent competitive landscape and the emerging players expected to significantly alter the market positioning of the current
market leaders. Most importantly, the report provides valuable insights on the pipeline products within the global Acne Therapeutics sector. This report is built using data and information sourced from proprietary databases, primary and secondary research and in-house analysis by GlobalData’s team of industry experts.

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Source:Rajesh Gunnam
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Tags:Acne Therapeutics, Pharmaceuticals_and_healthcare
Industry:Health
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