EZClick™ Glycoprotein Assay Kits

MILPITAS, Calif. - Dec. 1, 2017 - PRLog -- Glycoproteins are grouped by the type of linkage site. N-linked glycosylation occurs on Asparagine residues, while O-linked glycosylation takes place on serine and/or threonine residues. More than 50% of proteins undergo glycosylation during co- or post- translational processes. O-GlcNAc glycosylated proteins are implicated in normal brain functions, neurodegeneration, and type II diabetes, GalNAc-(Ser/Thr) is part of the Tn-antigen, an oncofetal antigen, overexpressed in cancerous conditions and cell-surface sialylated proteins found in tumors are associated with tumor invasion. BioVision is proud to offer three novel, yet highly specific EZClick™ Assay Kits detecting glycosylated proteins having Sialic Acid, O-GlcNAc, and/or GalNAc moieties. Our products are simple, with robust methods for labeling and detection of N-Linked and or O-linked glycosylation of cell surface proteins.

Key Features:

• Non-radioactive, versatile assays (Flow cytometry and Fluorescence Microscopy)

• Specific, homogeneous assay

• Sensitive: fluorometric format

• Convenient: minimal sample preparation, fast protocols < 2 hours

• Cost effective: 100 assays; High Throughput Screening (HTS) compatible

• Adaptable: works with most of the commonly available instrumentations

Kit # =       K441-100   K560-100    K714-100

Target=      NANA        GalNAc      GlcNAc

Click Label= Ac4ManAz   Ac4GalAz    Ac4GlcNAz

Size=          100 assays

Cells=         Suspension/Adherent

Applications=Fluorescence Microscopy/Flow Cytometry

Ex/Em (FACS) nm= 488/(530/590)

Ex/Em (FC) nm=(440/490)/(540/580)

Rxn Time =30 min

Click to get complete information about thiese kits: https://www.biovision.com/catalogsearch/result/?q=Glyco

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