Low Cell Adhesion Products for Highest Demands - PrimeSurface® by S-BIO, distributed by MoBiTec

GÖTTINGEN, Germany - March 22, 2018 - PRLog -- PrimeSurface® 3D Culture Spheroid plates: Ultra-low Attachment (ULA) Plates - Form Uniform Spheroids with Ultra-low Attachment PrimeSurface® Cell Culture Plates

PrimeSurface® cultureware are ultra-low attachment (ULA) dishes and plates that promote scaffold-free self-assembly of three-dimensional cellular spheroids. The plates are pre-coated with a unique ultra-hydrophilic polymer that enables spontaneous spheroid formation of uniform size and shape. The ULA plates have high optical clarity making them highly suitable for bright-field imaging and confocal microscopy. In addition to the widely used 96-well U-bottom plate, 96-well plates are also available with V- and M-bottom, giving scientist a choice to form tighter spheroids that are needed for specific cell types. For high-throughput screening (HTS) needs, 384-well plates are available in clear and white.

Features

• Ideal tool for uniform spheroid cell formation
• Ideal tool for differentiation and stimulation response studies
• Inducer reagent for differentiation can be applied after embryoid body (EB) formation of ES cells
• The formation of uniform spheroid cell clusters is due to the inhibition of  cell adhesion to plastic by a unique surface-coating technique
• Stable chemical bonding of the ultra-hydrophilic coating polymer
• No elution of chemicals from substrate during cell culture

Applications

Medical Research Institutions & Laboratories

Cell Culture

For Stem Cell Research:

Induction of ES, iPS, and mesenchymal stem cells differentiation from embryoid body formation.

For Drug Screening Research & Development:

An ideal product for drug response studies. Three-dimensional spheroid models are, physiologically, more relevant than two-dimensional monolayer models.

Grow uniform spheroids and screen for drug response in 96- and 384-well plates.

384-well white plates are suitable for chemiluminescence assay screening.

Compatible with bright-field and fluorescence Imaging systems:

• Celigo® by Nexcelom
• Spheroid applications on IncuCyte® by Sartorius
• Cytation 5 by BioTek

Experimental approach:

For tissue engineering and regenerative medicine via Regenova, a novel robotic system that facilitates the fabrication of three-dimensional cellular structures by placing cellular spheroids in fine needle arrays according to pre-designed 3D data. Experiments were performed with S-BIO's PrimeSurface™ 96U plates. More data on request.

Also available are PDFs on:

• Stem Cell Spheroid Formation with PrimeSurface
• PrimeSurface Anticancer Drug screening by: Spheroid Cell Culture

S-BIO products are distributed in Europe by MoBiTec, Germany: http://www.mobitec.com

Contact us for free samples of PrimeSurface® at info@mobitec.com !

About MoBiTec GmbH

MoBiTec GmbH (Goettingen, Germany) is a privately held company (founded in 1987) that offers research tools for molecular and cell biology. Products include DNA vectors for cloning and expression, cell transfection reagents and cell culture tools, immobilized and soluble enzymes, products for genomics and proteomics research, numerous antibodies and recombinant proteins, superior fluorescence reagents and kits, affinity chromatography products, as well as general laboratory equipment.

In parallel to its own product lines, MoBiTec distributes products from international companies in Germany. MoBiTec products are distributed worldwide, in Germany from their home office, in other countries by distributors.