Creative Biostructure Released Cryo-EM Based Particle Morphology Analysis Service

SHIRLEY, N.Y. - March 7, 2022 - PRLog -- Creative Biostructure, a biotechnology company that specialized in providing cost-effective services to scientists in the field of structural biology, now provides cryo-em based particle morphology analysis service (https://www.creative-biostructure.com/particle-morphology-analysis.htm) for the structural analysis of mixed liposome and exosome nanoparticles.

Cryo-electron microscopy (cryo-EM) particle analysis technology has become a new force in structural biology and plays an increasingly important role in the structural analysis of mixed liposomes and exosome nanoparticles. Basic information about the nature and source of particulate matter can often be gathered from the size, shape, and/or surface form of individual particles.

Using cryo-EM, the particle morphology can be analyzed and the protein structure when bound to small molecules can be obtained, which plays an important role in the development of medicinal chemistry. Scientists at Creative Biostructure are working hard to learn from the world's top laboratories and build cryo-EM (https://www.creative-biostructure.com/cryo-em.htm) teams.

The particle morphology analysis at Creative Biostructure is based on the principle that when frozen samples of tiny particles are placed under EM, they are nondestructively bombarded by a precisely focused electron beam (probe). The most commonly used emission signals in particle morphology analysis are secondary electrons, characteristic X-rays, and backscattered electrons. The secondary electrons generated from frozen particle samples are often used to characterize particle morphology. When the sample is irradiated by a primary electron flow, various interactions occur with the atoms in the sample. Therefore, the sample emits various forms of radiation that can be used to determine its composition after testing and processing.

EM platform at Creative Biostructure develops a particle morphology characterization system that can analyze the shape and size of individual particles ranging in size from 40 nm to 2,000 nm, distinguish individual particles or polymers, quantify the structure in polymers, analyze spheres or non-spheres, and calculate the number mixture of individual particles.

"Our cryo-EM team has rich experience in the processing and identification of lipid nanoparticles (https://www.creative-biostructure.com/lipid-nanoparticle-...), liposomes, exosomes, emulsion, and virus-like particles." Said Joanna, the chief marketing staff at Creative Biostructure.

Visit https://www.creative-biostructure.com/particle-morphology-analysis.htm to get more information about the particle morphology analysis service provided by Creative Biostructure.